David L. Brown, M.D.

• Peripheral Nerve Surgery
• Reconstructive Microsurgery
• Chronic Neuropathic Pain
• Lower Extremity Nerve Surgery
• Chest Wall, Groin & Abdominal Nerve Pain
• Low Back and Buttock Pain Nerve Surgery
• Post-Surgical Nerve Injury
• Post Mastectomy Nerve Surgery

Dr. Brown evaluates and treats complex peripheral nerve conditions including:

• Peripheral nerve injury and entrapment
• Chronic neuropathic pain
• Post-traumatic peripheral nerve conditions
• Post-surgical nerve injury and pain
• Neuromas
• CRPS and suspected peripheral nerve involvement
• Lower-extremity nerve conditions
• Chronic nerve pain following knee and hip replacement
• Foot and ankle nerve injury and entrapment
• Chest wall and post-mastectomy nerve pain
• Groin and post-hernia nerve pain
• Abdominal nerve pain, including ACNES
• Cluneal nerve-related low-back and buttock pain
• Shingles and postherpetic neuralgia

Dr. Brown received his medical degree from Vanderbilt University.

He completed his General Surgery Residency at the University of Cincinnati Hospitals and his Plastic Surgery Fellowship at the University of Michigan.

Dr. Brown then completed advanced fellowship training in reconstructive microsurgery at St. Vincent’s Hospital in Melbourne, Australia.

His training in plastic and reconstructive surgery and reconstructive microsurgery provides a broad foundation for evaluating complex peripheral nerve disorders, particularly those involving nerve injury, reconstruction, chronic pain and complications following trauma or previous surgery.

Dr. Brown has held significant national leadership positions in both plastic surgery and peripheral nerve surgery.

He is a Past President of the American Society for Peripheral Nerve and has served on the Board of Directors of the American Society of Plastic Surgeons. He has also served as President of the Michigan Academy of Plastic Surgeons and Parliamentarian of the Plastic Surgery Research Council.

Dr. Brown also serves as an Oral Boards Examiner for the American Board of Plastic Surgery, the same board through which he maintains his certification in plastic surgery.In this role, he participates in the evaluation of surgeons seeking board certification in the specialty.

He has authored or contributed to more than 70 scientific journal articles and 10 book chapters and has presented his research and clinical work internationally. His published work includes peripheral nerve injury and reconstruction, neuroma management, chronic neuropathic pain, post-mastectomy pain and neuropathic knee pain.

Dr. Brown has also co-authored multiple editions of The Michigan Manual of Plastic Surgery and has received multiple honors for surgical education and teaching.

Dr. Brown’s professional affiliations and leadership have included:

• American Society for Peripheral Nerve — Past President
• American Society of Plastic Surgeons — Former Board of Directors
• American Board of Plastic Surgery — Oral Boards Examiner
• American Association of Plastic Surgeons
• American Society for Reconstructive Microsurgery
• Michigan Academy of Plastic Surgeons — Past President
• Plastic Surgery Research Council — Former Parliamentarian

Dr. Brown’s board certification in plastic and reconstructive surgery, advanced training in reconstructive microsurgery and extensive peripheral nerve experience provide a specialized foundation for evaluating injuries and conditions involving the peripheral nervous system.

His medical-legal evaluations may include:

• Independent Medical Examinations
• Second opinions
• Medical record review
• Peripheral nerve injury and entrapment
• Post-traumatic nerve conditions
• Post-surgical nerve injury and chronic pain
• CRPS and suspected peripheral nerve involvement
• Causation
• Diagnosis and treatment recommendations
• Reasonableness and necessity of treatment
• Maximum medical improvement
• Impairment and disability evaluation
• Deposition and expert testimony

• State-of-the-Art Techniques in Treating Peripheral Nerve Injury. Kubiak CA, Kung TA, Brown DL, Cederna PS, Kemp SWP: Plast Reconstr Surg 141(3): 702-710, 2018. 
• Current State of the Surgical Treatment of Terminal Neuromas. Ives GC, Kung TA, Nghiem BT, Ursu DC, Brown DL, Cederna PS, Kemp SWP: Neurosurgery 83(3): 354-364, 2018.
• Principles of nerve repair and reconstruction and neuroma management. Kubiak CA, Brown DL: Grabb and Smith’s Plastic Surgery, Wolters Kluwer, 10, 87-96, 2019. 
• Dermatosensory Peripheral Nerve Interfaces: Prevention of Pain Recurrence Following Sensory Neurectomy. Hart SE, Brown DL: Hand Clin 37(3): 383-389, 2021. 
• Unmasked Neuropathic Pain After Neurectomy: A Case Series and Review of the Literature. Gomez-Rexrode AE, Kennedy SH, Brown DL: Plast Reconstr Surg Glob Open.11(8): e5221, 2023. 
• Management of Neuropathic Pain with Neurectomy Combined with Dermal Sensory Regenerative Peripheral Nerve Interface (DS-RPNI). Hespe GE, Brown DL: Semin Plas Surg.19;38(1):48-52. 2024 PMID: 38495065.
• Discussion: Efficacy of Surgical Treatment of Migraine Headaches Involving the Auriculotemporal Nerve (Site V). Brown DL: Plastic and Reconstructive Surgery 143(2): 564-565, 
• Surgical Approach to Injuries of the Cervical Plexus and Its Peripheral Nerve Branches. Brown DL, Dellon AL: Plast Reconstr Surg 141(4): 1021-1025, 2018. 
• Quadrangular space syndrome associated with superficial radial sensory neuropathy. Brown DL, Chung KC: Ann Plast Surg 43(2): 207-210, 1999. 
• Acute exertional compartment syndrome of the forearm. Dhawan V, Borschel GH, Brown DL: J Trauma 64(6): 1635-1637, 2008. 
• Effective Treatment of Chronic Mastectomy Pain with Intercostal Sensory Neurectomy. Hart S, Agarwal S, Hamill JB, Brown DL: Plastic and Reconstructive Surgery 14:5: 876-80, 2022. 
• Chronic Neuropathic Knee Pain Treated with Peripheral Nerve Operations Combined with Regenerative Peripheral Nerve Interfaces. Cinotto G, Hamill JB, Cederna PS, Kemp SWP, Brown DL: Plastic and Reconstructive Surgery. 
• Regenerative Peripheral Nerve Interfaces for the Treatment of Postamputation Neuroma Pain: Woo SL, Kung TA, Brown DL, Leonard JA, Kelly BM, Cederna PS: A Pilot Plast Reconstr Surg Glob Open 4(12): e1038, 2016. 
• Regenerative Peripheral Nerve Interfaces for the Management of Symptomatic Hand and Digital Neuromas. Hooper RC, Cederna PS, Brown DL, Haase SC, Waljee JF, Egeland BM, Kelley BP, Kung TA: Plast Reconstr Surg Glob Open 8(6): e2792, 2020.  
• Tarsal Tunnel. Lyons DA, Brown DL: Neurosurgery by Example, Peripheral Nerve Volume, Selden ed; Yang and Wilson vol ed Oxford University Press, Ny, NY, 2017. 
• Lower Extremity Contemporary Neuroma Management, Felder JM, Ko JH, Brown DL: Eberlein, Ed.; Springer, 2023. 
• Immediate and delayed nerve repair: improved muscle mass and function with leukemia inhibitory factor. Brown DL, Bennett TM, Dowsing BJ, Hayes A, Abate M, Morrison WA: J Hand Surg Am 27(6): 1048- 55, 2002.
• Neurotization of in vivo tissue engineered contractile, vascularized, 3-dimensional skeletal muscle. Dhawan V, Huang Y-C, Dow D, Birla RK, Brown DL: Plastic and Reconstructive Surgery 16 (3S): 179-80, 2005.  
• Short-term anti-CD40 ligand costimulatory blockade induces tolerance to peripheral nerve allografts, resulting in improved skeletal muscle. Brown DL, Bishop DK, Wood SY, Cederna PS: Plast Recon Surg 117(7): 2250-2258, 2006. 
• Neurotization improves contractile forces of tissue- engineered skeletal muscle. Dhawan V, Lytle IF, Dow DE, Huang YC, Brown DL: Tissue Eng. 13(11): 2813-2821, 2007.  
• Anti-CD40L monoclonal antibody treatment induces long-term, tissue-specific, immunologic hyporesponsiveness to peripheral nerve allografts. Mungara AK, Brown DL, Bishop DK, Wood SY, Cederna PS:  J Reconstr Microsurg 24(3): 189-195, 2008. 
• Systematic Approach to the Management of Neuropathic Groin Pain: A 20-year Retrospective Cohort Study: Kevin M. Klifto, DO, PharmD, William D. Henderson, MA, Miguel I. Dorante, MD, MBE, David L. Brown, MD & Robert R. Hagan, MD
• Groin Pain Involving the Genitofemoral Nerve: A 20 Year Experience
  Miguel I Dorante, MD, MBE¹, Kevin M Klifto, DO, PharmD², David L Brown, MD³; Robert R Hagan, MD³ (¹)Neuropax Clinic, St Louis, MO, (²)University of Missouri, Columbia, MO, (³)Neuropax Clinic, St. Louis, MO
• Unmasked neuropathic groin pain: risk of reoperation – Kevin M. Klifto, Miguel I. Dorante, William D. Henderson, David L Brown,  Robert R. Hagan
• Systematic Approach to the Management of Neuropathic Groin Pain: A 20-year Retrospective Cohort Study – Kevin M Klifto, William D. Henderson, Miguel I Dorante, David L Brown, Robert R Hagan